Cheese Tortellini Pepperoni Pizza

This Cheese Tortellini Pepperoni Pizza Casserole is a weeknight lifesaver and a comfort food dream come true. It combines the best things about pizza—ooey-gooey cheese, zesty pizza sauce, crispy pepperoni—baked into a cozy pasta dish that everyone will be fighting over.

I first made this on a busy weeknight and was amazed how fast it came together. Now it’s a regular at our dinner table because the kids keep asking for it.

Ingredients

• Cheese tortellini: fresh or frozen for that melty, cheese-filled goodness
• Pizza sauce: that brings bright tomato flavors and herbs—choose a quality jar for the best taste
• Sliced pepperoni: for the signature pizza bite, turkey or plant-based versions work too
• Shredded mozzarella cheese: for gooey meltiness on top and throughout
• Italian cheese blend: optional for extra cheesy complexity
• Italian seasoning: optional for that classic herb touch
• Garlic powder: optional adds subtle warmth
• Red pepper flakes: optional for a hint of heat
• Fresh basil or parsley: optional for garnish and fresh color

Step-by-Step Instructions

Preheat Oven:

Set your oven to 375 degrees Fahrenheit and lightly grease a 9 by 13-inch baking dish so the casserole won’t stick.

Cook the Tortellini:

Bring a large pot of salted water to a boil. Cook the tortellini according to the package instructions until just al dente to avoid mushiness after baking. Drain well and set aside.

Mix the Casserole:

In a large mixing bowl, combine the cooked tortellini, pizza sauce, half the mozzarella, and pepperoni slices. If you like, add Italian seasoning, garlic powder, and red pepper flakes. Stir everything gently but thoroughly until the tortellini are evenly coated.

Assemble:

Pour the mixture into the prepared baking dish and spread it evenly. Sprinkle the remaining mozzarella and Italian cheese blend on top for a bubbly, golden crust.

Bake:

Place the dish uncovered in the preheated oven. Bake for 20 to 25 minutes until the cheese is melted, bubbly, and spots of light golden brown form on top.

Garnish and Serve:

Let the casserole cool for a few minutes. Sprinkle fresh basil or parsley on top for a bright finish. Serve warm and savor the perfect pizza-pasta mashup.

Save Pin

The fresh basil really makes this dish pop, cutting through the richness and adding a fresh herbal note. I remember the first time I served this at a family gathering everyone was asking for seconds and thirds.

Storage Tips

Let the casserole cool thoroughly before covering tightly with foil or storing it in an airtight container. Refrigerate for up to four days. For freezing, assemble but do not bake. Wrap securely then freeze for up to three months. When ready, bake directly from frozen adjusting the cooking time.

Ingredient Substitutions

Tortellini can be swapped for ravioli or short pasta like penne. Pepperoni can be replaced with turkey pepperoni or vegetarian slices. Pizza sauce can be switched for marinara or spaghetti sauce. Add sautéed vegetables like mushrooms, bell peppers, or olives for extra layers of flavor.

Serving Suggestions

Pair with a crisp Caesar or arugula salad to balance richness. Garlic bread or breadsticks make the dish feel extra special. Roasted broccoli or zucchini work great as a simple vegetable side. A glass of red wine or sparkling water with lemon enhances the meal.

Cultural Context

This dish is a fantastic example of comfort food fusion, combining beloved Italian-American pizza flavors with a classic baked pasta style. It reflects the joy of turning favorite tastes into easy, family-friendly meals.

Pro Tips

• Avoid overcooking the tortellini or it will get mushy in the oven
• Use a quality pizza sauce because it forms the flavor backbone
• Layer cheese on top to get that golden bubbly crust everyone loves

Commonly Asked Questions

→ Can I prepare this dish ahead of time?

Yes, you can assemble the dish a day before, refrigerate it covered, and bake it fresh when ready.

→ Is this suitable for kids?

Absolutely, the cheesy, familiar flavors are a hit with children and make mealtime easy.

→ What pasta alternatives work well here?

Short pastas like penne, ziti, or rigatoni can replace tortellini if needed.

→ Can I make a vegetarian version?

Definitely. Simply omit the pepperoni or use a plant-based substitute to keep it meat-free.

→ How do I store and reheat leftovers?

Cool completely before refrigerating in an airtight container up to 4 days. Reheat in microwave or oven until warmed through.

→ What are some topping ideas to customize this bake?

Try adding sautéed mushrooms, bell peppers, olives, spinach, or cooked sausage for extra flavor variety.